2. Long Acting Bronchodilator

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Effectiveness of Inhaled Combined Corticosteroid/Long-Acting Bronchodilator Treatment in Reducing COPD Exacerbations and Short-Acting Bronchodilator Use

• Objective: To compare budesonide/formoterol (BFC) and fluticasone propionate/salmeterol (FSC) in their ability to reduce COPD exacerbations using a novel risk stratification approach. • Design: Retrospective cohort study with propensity matching and stratification by short-acting beta2-agonist (SABA) use. • Participants: 7704 COPD patients identified using 2 U.S. health claims databases (stud...

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. . . . . To : : orol , a new long - acting bronchodilator for inhalation

11 1WW long-acting bronchodilaror for inllalario11. P. 1\rvidsson, S. Depts of Pulmonary Medicine and Qinical Phar· macology, Golhenburg University, Medical Dept, CIBA-Geigy, Sweden. LOfdalll, B. Melandcr, L Wdlrlan.dt~r, N. Svedmyr. The aim or thJs s tudy was to evaluate If treatment with Inhaled Is appreciated by a.~tbmatlcs and whether lt ClHL'>CS tacltyConespondence: C-G. Lofdahl, Re~stroms...

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Bronchodilator treatment of stable COPD: long-acting anticholinergics

Since airflow obstruction in chronic obstructive pulmonary disease (COPD) is to some extent reversible, bronchodilators play an important role in the maintenance treatment of COPD the more they reduce hyperinflation and, as a result, improve dyspnoea and exercise capacity. Since parasympathetic activity is the dominant reversible component of airflow obstruction in COPD, inhaled short-acting an...

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Long-acting bronchodilator use after hospitalization for COPD: an observational study of health insurance claims data

BACKGROUND Treatment of stable chronic obstructive pulmonary disease (COPD) with long-acting bronchodilator (LABD) medications is recommended by the 2014 Global initiative for chronic Obstructive Lung Disease (GOLD) guidelines. The primary objective of this study was to examine LABD prescription fills after a COPD-related hospitalization. METHODS This retrospective observational study used cl...

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Severe COPD Exacerbation Risk and Long-Acting Bronchodilator Treatments: Comparison of Three Observational Data Analysis Methods

OBJECTIVE Results from three observational methods for assessing effectiveness of long-acting bronchodilator therapies for reducing severe exacerbations of chronic obstructive pulmonary disease (COPD) were compared: intent-to-treat (ITT), as protocol (AP), and an as-treated analysis that utilized a marginal structural model (MSM) incorporating time-varying covariates related to treatment adhere...

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ژورنال

عنوان ژورنال: Nihon Naika Gakkai Zasshi

سال: 2008

ISSN: 0021-5384,1883-2083

DOI: 10.2169/naika.97.1228